Platelet Refractoriness Due to Anti-CD-36(NAKa) Ameliorated By Platelet Washing
نویسندگان
چکیده
منابع مشابه
Identification, Prevention and management of platelet refractoriness
Abstract Background and Objectives Platelet refractoriness can be caused by immunological and non-immunological factors. In non-immunological cases, the source which is usually a disease, should be eliminated. In immunological cases antibodies produced against foreign platelet antigens play a significant role. The aim of this review was to investigate the strategies involved in identifying ...
متن کاملPlatelet Refractoriness and how it is formed
Abstract Background and Objectives Transfusion of platelet has become one of the main treatments for thrombocytopenic patients to reduce the severity and frequency of bleeding consequences. Failure to attain the desired level of platelets in a patient following platelet transfusion is defined as platelet refractoriness. The purpose of present paper is to review and study the mechanisms involve...
متن کاملEvaluation of platelet antigens and antibodies in patients with platelet refractoriness
Abstract Background and Objectives Immune platelet refractoriness is a complication of blood transfusion in patients with multiple platelet transfusions. Antibodies against surface antigens, including human platelet antigens (HPAs) and human leukocyte antigens (HLAs), can be produced which can cause the degradation of transfused platelets by macrophages. In this study, the frequency of platele...
متن کاملRefractoriness to platelet transfusion after single-donor consecutive platelet transfusions and its relationship to platelet antibodies.
In thirty patients with acute leukemia and severe aplastic anemia receiving random single donor platelet transfusions, the development of refractoriness by consecutive platelet transfusions with cytapheresis and its relationship to the appearance of anti-platelet antibodies were investigated. The median number of platelet transfusions inducing refractoriness was 13 times, and 20% of the patient...
متن کاملAlloimmunization and Refractoriness to Allogeneic Platelet Transfusions
F OUR YEARS AGO an editorial in Blood identified a number of issues concerning policy decision-making about the clinical use of leukodepleted cellular blood products to prevent HLA-alloimmunization and refractoriness to transfused allogeneic platelets.’ In that editorial, Schiffer concluded that it was premature to recommend platelet leukodepletion for routine use. The issues identified in that...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 2016
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v128.22.3857.3857